Excellent. A lot of these diseases like Alzheimer's are prion diseases. Meaning, proteins are misfolded. One of my earliest research projects was to study a protein called Apomyoglobin (without the Iron) and determine its structure as the chain length changes. So somewhere a pathway of the protein folding is being disrupted either during translation or post translationally when either the chemistry of the cell changes or some other regulator is off. Vitamin D is an interesting piece in the mix. Look for papers, where vitamin D in general affects protein structures and may be you can make a correlation.
Excellent. A lot of these diseases like Alzheimer's are prion diseases. Meaning, proteins are misfolded. One of my earliest research projects was to study a protein called Apomyoglobin (without the Iron) and determine its structure as the chain length changes. So somewhere a pathway of the protein folding is being disrupted either during translation or post translationally when either the chemistry of the cell changes or some other regulator is off. Vitamin D is an interesting piece in the mix. Look for papers, where vitamin D in general affects protein structures and may be you can make a correlation.